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C8 β Polyclonal Antibody

商品貨號(hào)： PLA019396

適應(yīng) 性： 人,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

在線咨詢

MSDS

說(shuō)明書

商品描述

基因名稱： C8B
蛋白名稱： C8 β
Human_gene_id： 732
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=732
Human_swiss_prot_no： P07358
Human_swiss_link： http://www.uniprot.org/uniprotkb/P07358/entry
Mouse_gene_id： 110382
Mouse_swiss_prot_no： Q8BH35
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8BH35
Rat_swiss_prot_no： P55314
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P55314
特異性： C8 β Polyclonal Antibody detects endogenous levels of C8 β
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000, ELISA 1:10000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Complement component C8 beta chain (Complement component 8 subunit beta)
實(shí)測(cè)條帶： 70kD
信號(hào)通路： Complement and coagulation cascades;Prion diseases;Systemic lupus erythematosus;
功能： disease:Defects in C8B are a cause of complement C8 deficiency type II [MIM:120960]. Patients with deficiency of C8 suffer from recurrent bacterial infections, predominantly from Neisseria meningitidis.,function:C8 is a constituent of the membrane attack complex. C8 binds to the C5b-7 complex, forming the C5b-8 complex. C5-b8 binds C9 and acts as a catalyst in the polymerization of C9.,online information:C8B mutation db,polymorphism:The sequence shown is that of allotype C8B B.,PTM:N-glycosylated; contains one or two bound glycans. Not O-glycosylated.,similarity:Belongs to the complement C6/C7/C8/C9 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 1 MACPF domain.,similarity:Contains 2 TSP type-1 domains.,subunit:C8 is composed of three chains: alpha, beta and gamma. The beta chain binds to the C8 alpha chain and to the C5b-C7 complex, presumably to C5b. It is essential to the incorporation of C8 into the C5b-C8 complex.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Secreted.
組織表達(dá)： Liver,Plasma,
科研貨號(hào)： PLA019396

C8 β Polyclonal Antibody

Catalog No PLA019396

Product information

基因名稱： C8B
蛋白名稱： C8 β
Human_gene_id： 732
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=732
Human_swiss_prot_no： P07358
Human_swiss_link： http://www.uniprot.org/uniprotkb/P07358/entry
Mouse_gene_id： 110382
Mouse_swiss_prot_no： Q8BH35
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8BH35
Rat_swiss_prot_no： P55314
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P55314
特異性： C8 β Polyclonal Antibody detects endogenous levels of C8 β
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000, ELISA 1:10000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Complement component C8 beta chain (Complement component 8 subunit beta)
實(shí)測(cè)條帶： 70kD
信號(hào)通路： Complement and coagulation cascades;Prion diseases;Systemic lupus erythematosus;
功能： disease:Defects in C8B are a cause of complement C8 deficiency type II [MIM:120960]. Patients with deficiency of C8 suffer from recurrent bacterial infections, predominantly from Neisseria meningitidis.,function:C8 is a constituent of the membrane attack complex. C8 binds to the C5b-7 complex, forming the C5b-8 complex. C5-b8 binds C9 and acts as a catalyst in the polymerization of C9.,online information:C8B mutation db,polymorphism:The sequence shown is that of allotype C8B B.,PTM:N-glycosylated; contains one or two bound glycans. Not O-glycosylated.,similarity:Belongs to the complement C6/C7/C8/C9 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 1 MACPF domain.,similarity:Contains 2 TSP type-1 domains.,subunit:C8 is composed of three chains: alpha, beta and gamma. The beta chain binds to the C8 alpha chain and to the C5b-C7 complex, presumably to C5b. It is essential to the incorporation of C8 into the C5b-C8 complex.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Secreted.
組織表達(dá)： Liver,Plasma,
科研貨號(hào)： PLA019396

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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