功能: alternative products:Additional isoforms seem to exist,disease:Produced by many tumors from patients with HHM (humoral hypercalcemia of malignancy).,function:Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth.,function:Osteostatin is a potent inhibitor of osteoclastic bone resorption.,PTM:There are 3 principal secretory forms, called PTHrP[1-36], PTHrP[38-94], and osteostatin (PTHrP[107-139]) arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.,similarity:Belongs to the parathyroid hormone family.,tissue specificity:Ubiquitous. Also expressed in the mammary gland.,
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細(xì)胞定位: Cytoplasm. Nucleus. Secreted.
組織表達(dá): Ubiquitous. Also expressed in the mammary gland.
功能: alternative products:Additional isoforms seem to exist,disease:Produced by many tumors from patients with HHM (humoral hypercalcemia of malignancy).,function:Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth.,function:Osteostatin is a potent inhibitor of osteoclastic bone resorption.,PTM:There are 3 principal secretory forms, called PTHrP[1-36], PTHrP[38-94], and osteostatin (PTHrP[107-139]) arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.,similarity:Belongs to the parathyroid hormone family.,tissue specificity:Ubiquitous. Also expressed in the mammary gland.,
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細(xì)胞定位: Cytoplasm. Nucleus. Secreted.
組織表達(dá): Ubiquitous. Also expressed in the mammary gland.
科研貨號: PLA019392
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