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LIFR Polyclonal Antibody

商品貨號： PLA019239

適應(yīng) 性： 人,大鼠,小鼠,

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： LIFR
蛋白名稱： Leukemia inhibitory factor receptor
Human_gene_id： 3977
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3977
Human_swiss_prot_no： P42702
Human_swiss_link： http://www.uniprot.org/uniprotkb/P42702/entry
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Mouse_swiss_prot_no： P42703
Mouse_swiss_link： http://www.uniprot.org/uniprot/P42703
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat_swiss_link： http://www.uniprot.org/uniprot/
特異性： LIFR Polyclonal Antibody detects endogenous levels of LIFR protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： LIFR; Leukemia inhibitory factor receptor; LIF receptor; LIF-R; CD118
實測條帶： 120kD
信號通路： Cytokine-cytokine receptor interaction;Jak_STAT;
功能： disease:A chromosomal rearrangement involving LIFR may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(5;8)(p13;q12) with PLAG1.,disease:Defects in LIFR are the cause of Stueve-Wiedemann syndrome (SWS) [MIM:601559]; also called Schwartz-Jampel syndrome type 2 or SJS2. SWS is a severe autosomal recessive condition and belongs to the group of the bent-bone dysplasias. SWS is characterized by bowing of the lower limbs, with internal cortical thickening, wide metaphyses with abnormal trabecular pattern, and camptodactyly. Additional features include feeding and swallowing difficulties, as well as respiratory distress and hyperthermic episodes, which cause death in the first months of life. The rare survivors develop progressive scoliosis, spontaneous fractures, bowing of the lower limbs, with prominent joints and dysautonomia symptoms, including temperature instability, absent corneal and patellar reflexes, and smooth tongue.,domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.,similarity:Belongs to the type I cytokine receptor family. Type 2 subfamily.,similarity:Contains 6 fibronectin type-III domains.,subunit:Heterodimer composed of LIFR and IL6ST. The heterodimer formed by LIFR and IL6ST interacts with the complex formed by CNTF and CNTFR.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
組織表達： Hippocampus,Placenta,
科研貨號： PLA019239

LIFR Polyclonal Antibody

Catalog No PLA019239

Product information

基因名稱： LIFR
蛋白名稱： Leukemia inhibitory factor receptor
Human_gene_id： 3977
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3977
Human_swiss_prot_no： P42702
Human_swiss_link： http://www.uniprot.org/uniprotkb/P42702/entry
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Mouse_swiss_prot_no： P42703
Mouse_swiss_link： http://www.uniprot.org/uniprot/P42703
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat_swiss_link： http://www.uniprot.org/uniprot/
特異性： LIFR Polyclonal Antibody detects endogenous levels of LIFR protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： LIFR; Leukemia inhibitory factor receptor; LIF receptor; LIF-R; CD118
實測條帶： 120kD
信號通路： Cytokine-cytokine receptor interaction;Jak_STAT;
功能： disease:A chromosomal rearrangement involving LIFR may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(5;8)(p13;q12) with PLAG1.,disease:Defects in LIFR are the cause of Stueve-Wiedemann syndrome (SWS) [MIM:601559]; also called Schwartz-Jampel syndrome type 2 or SJS2. SWS is a severe autosomal recessive condition and belongs to the group of the bent-bone dysplasias. SWS is characterized by bowing of the lower limbs, with internal cortical thickening, wide metaphyses with abnormal trabecular pattern, and camptodactyly. Additional features include feeding and swallowing difficulties, as well as respiratory distress and hyperthermic episodes, which cause death in the first months of life. The rare survivors develop progressive scoliosis, spontaneous fractures, bowing of the lower limbs, with prominent joints and dysautonomia symptoms, including temperature instability, absent corneal and patellar reflexes, and smooth tongue.,domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.,similarity:Belongs to the type I cytokine receptor family. Type 2 subfamily.,similarity:Contains 6 fibronectin type-III domains.,subunit:Heterodimer composed of LIFR and IL6ST. The heterodimer formed by LIFR and IL6ST interacts with the complex formed by CNTF and CNTFR.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
組織表達： Hippocampus,Placenta,
科研貨號： PLA019239

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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