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AID Polyclonal Antibody

商品貨號： PLA019206

適應性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： AICDA
蛋白名稱： Activation-induced cytidine deaminase
Human_gene_id： 57379
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57379
Human_swiss_prot_no： Q9GZX7
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9GZX7/entry
Mouse_gene_id： 11628
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11628
Mouse_swiss_prot_no： Q9WVE0
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9WVE0
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat_swiss_link： http://www.uniprot.org/uniprot/
特異性： AID Polyclonal Antibody detects endogenous levels of AID protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： AICDA; AID; Activation-induced cytidine deaminase; Cytidine aminohydrolase
實測條帶： 24kD
信號通路： Intestinal immune network for IgA production;Primary immunodeficiency;
功能： catalytic activity:Cytidine + H(2)O = uridine + NH(3).,cofactor:Zinc.,disease:Defects in AICDA are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2) [MIM:605258]. HIGM2 is characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE, resulting in a profound susceptibility to bacterial infections. HIGM2 causes the absence of Ig class switch recombination (CSR), the lack of Ig somatic hypermutations, and lymph node hyperplasia caused by the presence of giant germinal centers.,function:RNA-editing deaminase involved in somatic hypermutation, gene conversion, and class-switch recombination. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses.,online information:AICDA mutation db,similarity:Belongs to the cytidine and deoxycytidylate deaminase family.,tissue specificity:Strongly expressed in lymph nodes and tonsils.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Nucleus . Cytoplasm . Predominantly cytoplasmic (PubMed:21385873). In the presence of MCM3AP/GANP, relocalizes to the nucleus (By similarity). .
組織表達： Strongly expressed in lymph nodes and tonsils.
科研貨號： PLA019206

AID Polyclonal Antibody

Catalog No PLA019206

Product information

基因名稱： AICDA
蛋白名稱： Activation-induced cytidine deaminase
Human_gene_id： 57379
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57379
Human_swiss_prot_no： Q9GZX7
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9GZX7/entry
Mouse_gene_id： 11628
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11628
Mouse_swiss_prot_no： Q9WVE0
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9WVE0
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat_swiss_link： http://www.uniprot.org/uniprot/
特異性： AID Polyclonal Antibody detects endogenous levels of AID protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： AICDA; AID; Activation-induced cytidine deaminase; Cytidine aminohydrolase
實測條帶： 24kD
信號通路： Intestinal immune network for IgA production;Primary immunodeficiency;
功能： catalytic activity:Cytidine + H(2)O = uridine + NH(3).,cofactor:Zinc.,disease:Defects in AICDA are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2) [MIM:605258]. HIGM2 is characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE, resulting in a profound susceptibility to bacterial infections. HIGM2 causes the absence of Ig class switch recombination (CSR), the lack of Ig somatic hypermutations, and lymph node hyperplasia caused by the presence of giant germinal centers.,function:RNA-editing deaminase involved in somatic hypermutation, gene conversion, and class-switch recombination. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses.,online information:AICDA mutation db,similarity:Belongs to the cytidine and deoxycytidylate deaminase family.,tissue specificity:Strongly expressed in lymph nodes and tonsils.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Nucleus . Cytoplasm . Predominantly cytoplasmic (PubMed:21385873). In the presence of MCM3AP/GANP, relocalizes to the nucleus (By similarity). .
組織表達： Strongly expressed in lymph nodes and tonsils.
科研貨號： PLA019206

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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