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DPYD Polyclonal Antibody

商品貨號： PLA018935

適應性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： DPYD
蛋白名稱： Dihydropyrimidine dehydrogenase [NADP(+)]
Human_gene_id： 1806
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1806
Human_swiss_prot_no： Q12882
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q12882/entry
Mouse_gene_id： 99586
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=99586
Mouse_swiss_prot_no： Q8CHR6
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8CHR6
Rat_gene_id： 81656
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81656
Rat_swiss_prot_no： O89000
Rat_swiss_link： http://www.uniprot.org/uniprot/O89000
特異性： DPYD Polyclonal Antibody detects endogenous levels of DPYD protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： DPYD; Dihydropyrimidine dehydrogenase [NADP(+)]; DHPDHase; DPD; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase
實測條帶： 120kD
信號通路： Pyrimidine metabolism;beta-Alanine metabolism;Pantothenate and CoA biosynthesis;Drug metabolism;
功能： catalytic activity:5,6-dihydrouracil + NADP(+) = uracil + NADPH.,cofactor:Binds 2 4Fe-4S clusters. Contains approximately 33 iron atoms per molecule.,cofactor:Binds 2 FAD.,cofactor:Binds 2 FMN.,disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) [MIM:274270]; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.,function:Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.,pathway:Amino-acid biosynthesis; beta-alanine biosynthesis.,similarity:Belongs to the dihydropyrimidine dehydrogenase family.,similarity:Contains 3 4Fe-4S ferredoxin-type domains.,subunit:Homodimer.,tissue specificity:Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.,
相關產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm.
組織表達： Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.
科研貨號： PLA018935

DPYD Polyclonal Antibody

Catalog No PLA018935

Product information

基因名稱： DPYD
蛋白名稱： Dihydropyrimidine dehydrogenase [NADP(+)]
Human_gene_id： 1806
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1806
Human_swiss_prot_no： Q12882
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q12882/entry
Mouse_gene_id： 99586
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=99586
Mouse_swiss_prot_no： Q8CHR6
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8CHR6
Rat_gene_id： 81656
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81656
Rat_swiss_prot_no： O89000
Rat_swiss_link： http://www.uniprot.org/uniprot/O89000
特異性： DPYD Polyclonal Antibody detects endogenous levels of DPYD protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： DPYD; Dihydropyrimidine dehydrogenase [NADP(+)]; DHPDHase; DPD; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase
實測條帶： 120kD
信號通路： Pyrimidine metabolism;beta-Alanine metabolism;Pantothenate and CoA biosynthesis;Drug metabolism;
功能： catalytic activity:5,6-dihydrouracil + NADP(+) = uracil + NADPH.,cofactor:Binds 2 4Fe-4S clusters. Contains approximately 33 iron atoms per molecule.,cofactor:Binds 2 FAD.,cofactor:Binds 2 FMN.,disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) [MIM:274270]; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.,function:Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.,pathway:Amino-acid biosynthesis; beta-alanine biosynthesis.,similarity:Belongs to the dihydropyrimidine dehydrogenase family.,similarity:Contains 3 4Fe-4S ferredoxin-type domains.,subunit:Homodimer.,tissue specificity:Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.,
相關產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm.
組織表達： Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.
科研貨號： PLA018935

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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