其他名稱: Dmrpa1;Drosophila Replication Protein A;DRPA;DSSB;HSSB;Human single stranded DNA binding protein;MST075;MSTP075;p70;REPA 1;REPA1;Replication factor A;Replication factor A protein 1;Replication protein A 70 kDa DNA-binding subunit;Replication protein A 70kDa DNA binding subunit;Replication protein A1 (70kD);Replication protein A1 (70kD); Replication protein A1 70kDa;Replication protein A1;RF A;RF-A protein 1;RFA;RFA1_HUMAN; RP A;RP-A p70;RPA 1;RPA 70;RPA;RPA1;Single stranded binding protein 70;Single stranded DNA binding protein;Single-stranded DNA-binding protein;Ssb70.
實測條帶: 70kD
信號通路: DNA replication;Nucleotide excision repair;Mismatch repair;Homologous recombination;
功能: function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,
相關產品: RS0001,RS0002,YM3028,YM3029
細胞定位: Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. .
其他名稱: Dmrpa1;Drosophila Replication Protein A;DRPA;DSSB;HSSB;Human single stranded DNA binding protein;MST075;MSTP075;p70;REPA 1;REPA1;Replication factor A;Replication factor A protein 1;Replication protein A 70 kDa DNA-binding subunit;Replication protein A 70kDa DNA binding subunit;Replication protein A1 (70kD);Replication protein A1 (70kD); Replication protein A1 70kDa;Replication protein A1;RF A;RF-A protein 1;RFA;RFA1_HUMAN; RP A;RP-A p70;RPA 1;RPA 70;RPA;RPA1;Single stranded binding protein 70;Single stranded DNA binding protein;Single-stranded DNA-binding protein;Ssb70.
實測條帶: 70kD
信號通路: DNA replication;Nucleotide excision repair;Mismatch repair;Homologous recombination;
功能: function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,
相關產品: RS0001,RS0002,YM3028,YM3029
細胞定位: Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. .