其他名稱： alpha pal;alpha palindromic binding protein;Alpha palindromic-binding protein;Alpha-pal; locus control region factor 1;NFE2 related factor 1;NRF-1;Nrf1;NRF1_HUMAN;Nuclear respiratory factor 1;transcription factor 11.
實測條帶： 72kD
信號通路： Huntington's disease;
功能： function:Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.,PTM:Phosphorylation enhances DNA binding.,similarity:Belongs to the NRF1/Ewg family.,subunit:Homodimer. Binds DNA as a dimer. Interacts with PPRC1.,tissue specificity:Ubiquitously expressed with strongest expression in skeletal muscle.,
其他名稱： alpha pal;alpha palindromic binding protein;Alpha palindromic-binding protein;Alpha-pal; locus control region factor 1;NFE2 related factor 1;NRF-1;Nrf1;NRF1_HUMAN;Nuclear respiratory factor 1;transcription factor 11.
實測條帶： 72kD
信號通路： Huntington's disease;
功能： function:Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.,PTM:Phosphorylation enhances DNA binding.,similarity:Belongs to the NRF1/Ewg family.,subunit:Homodimer. Binds DNA as a dimer. Interacts with PPRC1.,tissue specificity:Ubiquitously expressed with strongest expression in skeletal muscle.,
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