功能: function:Involved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.,similarity:Belongs to the CREC family.,similarity:Contains 6 EF-hand domains.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Interacts with GGCX.,tissue specificity:Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.,
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細(xì)胞定位: Endoplasmic reticulum membrane . Golgi apparatus . Secreted . Melanosome . Sarcoplasmic reticulum lumen . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
組織表達(dá): Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.
功能: function:Involved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.,similarity:Belongs to the CREC family.,similarity:Contains 6 EF-hand domains.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Interacts with GGCX.,tissue specificity:Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.,
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細(xì)胞定位: Endoplasmic reticulum membrane . Golgi apparatus . Secreted . Melanosome . Sarcoplasmic reticulum lumen . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
組織表達(dá): Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.
科研貨號(hào): PLA005263
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