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Hexokinase II mouse mAb

商品貨號(hào)： PLA005243

適應(yīng) 性： 大鼠,小鼠,猴

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： hk2
Human_gene_id： 3099
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3099
Human_swiss_prot_no： P52789
Human_swiss_link： http://www.uniprot.org/uniprotkb/P52789/entry
Mouse_swiss_prot_no： O08528
Mouse_swiss_link： http://www.uniprot.org/uniprot/O08528
特異性： This antibody detects endogenous levels of Hexokinase II and does not cross-react with related proteins.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： wb 1:500
純化工藝： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： DKFZp686M1669;Hexokinase 2;Hexokinase 2 muscle;Hexokinase type II;Hexokinase-2;HK 2;HK II;HK2;HKII;HxK 2;HxK2;HXK2_HUMAN;Muscle form hexokinase.
實(shí)測(cè)條帶： 102kD
信號(hào)通路： Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Insulin_Receptor;Type II diabetes mellitus;
功能： catalytic activity:ATP + D-hexose = ADP + D-hexose 6-phosphate.,domain:The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus.,enzyme regulation:Hexokinase is an allosteric enzyme inhibited by its product Glc-6-P.,miscellaneous:In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).,online information:Hexokinase entry,pathway:Carbohydrate metabolism; hexose metabolism.,polymorphism:Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.,similarity:Belongs to the hexokinase family.,subcellular location:Its hydrophobic N-terminal sequence may be involved in membrane binding.,subunit:Monomer.,tissue specificity:Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasm, cytosol . The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (PubMed:29298880). The interaction with the mitochondrial outer membrane via the mitochondrial-binding peptide (MBP) region promotes higher stability of the protein (PubMed:29298880). Release from the mitochondrial outer membrane into the cytosol induces permeability transition pore (PTP) opening and apoptosis (PubMed:18350175). .
組織表達(dá)： Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
tag： hot
科研貨號(hào)： PLA005243

Hexokinase II mouse mAb

Catalog No PLA005243

Product information

發(fā)貨日期： 7
基因名稱： hk2
Human_gene_id： 3099
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3099
Human_swiss_prot_no： P52789
Human_swiss_link： http://www.uniprot.org/uniprotkb/P52789/entry
Mouse_swiss_prot_no： O08528
Mouse_swiss_link： http://www.uniprot.org/uniprot/O08528
特異性： This antibody detects endogenous levels of Hexokinase II and does not cross-react with related proteins.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： wb 1:500
純化工藝： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： DKFZp686M1669;Hexokinase 2;Hexokinase 2 muscle;Hexokinase type II;Hexokinase-2;HK 2;HK II;HK2;HKII;HxK 2;HxK2;HXK2_HUMAN;Muscle form hexokinase.
實(shí)測(cè)條帶： 102kD
信號(hào)通路： Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Insulin_Receptor;Type II diabetes mellitus;
功能： catalytic activity:ATP + D-hexose = ADP + D-hexose 6-phosphate.,domain:The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus.,enzyme regulation:Hexokinase is an allosteric enzyme inhibited by its product Glc-6-P.,miscellaneous:In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).,online information:Hexokinase entry,pathway:Carbohydrate metabolism; hexose metabolism.,polymorphism:Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.,similarity:Belongs to the hexokinase family.,subcellular location:Its hydrophobic N-terminal sequence may be involved in membrane binding.,subunit:Monomer.,tissue specificity:Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasm, cytosol . The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (PubMed:29298880). The interaction with the mitochondrial outer membrane via the mitochondrial-binding peptide (MBP) region promotes higher stability of the protein (PubMed:29298880). Release from the mitochondrial outer membrane into the cytosol induces permeability transition pore (PTP) opening and apoptosis (PubMed:18350175). .
組織表達(dá)： Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
tag： hot
科研貨號(hào)： PLA005243

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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