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Aldose Reductase Monoclonal Antibody

商品貨號： PLA005091

適應性： 人,小鼠,狗,兔

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： AKR1B1
蛋白名稱： Aldose reductase
Human_gene_id： 231
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=231
Human_swiss_prot_no： P15121
Human_swiss_link： http://www.uniprot.org/uniprotkb/P15121/entry
Mouse_gene_id： 11677
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11677
Mouse_swiss_prot_no： P45376
Mouse_swiss_link： http://www.uniprot.org/uniprot/P45376
Rat_swiss_prot_no： P07943
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P07943
特異性： Aldose Reductase Monoclonal Antibody detects endogenous levels of Aldose Reductase protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： AKR1B1; ALDR1; Aldose reductase; AR; Aldehyde reductase; Aldo-keto reductase family 1 member B1
信號通路： Pentose and glucuronate interconversions;Fructose and mannose metabolism;Galactose metabolism;Glycerolipid metabolism;Pyruvate metabolism;
功能： catalytic activity:Alditol + NAD(P)(+) = aldose + NAD(P)H.,disease:In diabetes and galactosemia, increased AR activity leads to high levels of sorbitol and galactitol, respectively, in the cells of many tissues. Accumulation of sugar alcohols has been shown to cause osmotic cataracts in the lens. AR is also thought to play a key role in diabetic complications of three other target tissues, namely, nerve, kidney and retina.,enzyme regulation:Cys-299 may regulate the kinetic and inhibition properties of the enzyme, but does not participate in catalysis.,function:Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.,similarity:Belongs to the aldo/keto reductase family.,subunit:Monomer.,tissue specificity:Highly expressed in embryonic epithelial cells (EUE) in response to osmotic stress.,
相關產品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm.
組織表達： Highly expressed in embryonic epithelial cells (EUE) in response to osmotic stress.
科研貨號： PLA005091

Aldose Reductase Monoclonal Antibody

Catalog No PLA005091

Product information

發(fā)貨日期： 7
基因名稱： AKR1B1
蛋白名稱： Aldose reductase
Human_gene_id： 231
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=231
Human_swiss_prot_no： P15121
Human_swiss_link： http://www.uniprot.org/uniprotkb/P15121/entry
Mouse_gene_id： 11677
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11677
Mouse_swiss_prot_no： P45376
Mouse_swiss_link： http://www.uniprot.org/uniprot/P45376
Rat_swiss_prot_no： P07943
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P07943
特異性： Aldose Reductase Monoclonal Antibody detects endogenous levels of Aldose Reductase protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： AKR1B1; ALDR1; Aldose reductase; AR; Aldehyde reductase; Aldo-keto reductase family 1 member B1
信號通路： Pentose and glucuronate interconversions;Fructose and mannose metabolism;Galactose metabolism;Glycerolipid metabolism;Pyruvate metabolism;
功能： catalytic activity:Alditol + NAD(P)(+) = aldose + NAD(P)H.,disease:In diabetes and galactosemia, increased AR activity leads to high levels of sorbitol and galactitol, respectively, in the cells of many tissues. Accumulation of sugar alcohols has been shown to cause osmotic cataracts in the lens. AR is also thought to play a key role in diabetic complications of three other target tissues, namely, nerve, kidney and retina.,enzyme regulation:Cys-299 may regulate the kinetic and inhibition properties of the enzyme, but does not participate in catalysis.,function:Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.,similarity:Belongs to the aldo/keto reductase family.,subunit:Monomer.,tissue specificity:Highly expressed in embryonic epithelial cells (EUE) in response to osmotic stress.,
相關產品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm.
組織表達： Highly expressed in embryonic epithelial cells (EUE) in response to osmotic stress.
科研貨號： PLA005091

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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