功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,caution:It is uncertain whether Met-1 is the initiator.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subunit:Interacts with INPP5D/SHIP1 and INPPL1/SHIP2.,tissue specificity:Hematopoietic cell lines including myeloid, B-, and T-cell lineages.,
相關產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm. Cell membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Following B-cell or T-cell receptors activation by antigen, translocates to the plasma membrane through its PH domain. Thrombin and integrin engagement induces translocation of TEC to the cytoskeleton during platelet activation. In cardiac myocytes, assumes a diffuse intracellular localization under basal conditions but is recruited to striated structures upon various stimuli, including ATP (By similarity). .
組織表達： Expressed in a wide range of cells, including hematopoietic cell lines like myeloid, B-, and T-cell lineages.
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,caution:It is uncertain whether Met-1 is the initiator.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subunit:Interacts with INPP5D/SHIP1 and INPPL1/SHIP2.,tissue specificity:Hematopoietic cell lines including myeloid, B-, and T-cell lineages.,
相關產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm. Cell membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Following B-cell or T-cell receptors activation by antigen, translocates to the plasma membrane through its PH domain. Thrombin and integrin engagement induces translocation of TEC to the cytoskeleton during platelet activation. In cardiac myocytes, assumes a diffuse intracellular localization under basal conditions but is recruited to striated structures upon various stimuli, including ATP (By similarity). .
組織表達： Expressed in a wide range of cells, including hematopoietic cell lines like myeloid, B-, and T-cell lineages.
科研貨號： PLA005057
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