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PRAK Monoclonal Antibody

商品貨號： PLA004997

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： MAPKAPK5
蛋白名稱： MAP kinase-activated protein kinase 5
Human_gene_id： 8550
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8550
Human_swiss_prot_no： Q8IW41
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q8IW41/entry
Mouse_swiss_prot_no： O54992
Mouse_swiss_link： http://www.uniprot.org/uniprot/O54992
特異性： PRAK Monoclonal Antibody detects endogenous levels of PRAK protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： MAPKAPK5; PRAK; MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; p38-regulated/activated protein kinase; PRAK
信號通路： MAPK_ERK_Growth;MAPK_G_Protein;
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:p38 alpha and beta-dependent phosphorylation increases its activity. Activated by stress-related extracellular stimuli; such as H(2)O(2), arsenite, anisomycin TNF alpha and also PMA and the calcium ionophore A23187; but to a lesser extent. In vitro, activated by SQSTM1.,function:Mediates stress-induced small heat shock protein 27 phosphorylation.,PTM:Phosphorylated on Thr-182; which is the regulatory phosphorylation site and is located on the T-loop/loop 12.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Also observed in the nucleus.,subunit:Interacts with SQSTM1.,tissue specificity:Expressed ubiquitously.,
相關(guān)產(chǎn)品： YT3849,YT3848,YP0820,KA4169C,KA1752C
細(xì)胞定位： Cytoplasm. Nucleus. Translocates to the cytoplasm following phosphorylation and activation. Interaction with ERK3/MAPK6 or ERK4/MAPK4 and phosphorylation at Thr-182, activates the protein kinase activity, followed by translocation to the cytoplasm. Phosphorylation by PKA/PRKACA at Ser-115 also induces nuclear export.
組織表達(dá)： Expressed ubiquitously.
科研貨號： PLA004997

PRAK Monoclonal Antibody

Catalog No PLA004997

Product information

發(fā)貨日期： 7
基因名稱： MAPKAPK5
蛋白名稱： MAP kinase-activated protein kinase 5
Human_gene_id： 8550
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8550
Human_swiss_prot_no： Q8IW41
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q8IW41/entry
Mouse_swiss_prot_no： O54992
Mouse_swiss_link： http://www.uniprot.org/uniprot/O54992
特異性： PRAK Monoclonal Antibody detects endogenous levels of PRAK protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： MAPKAPK5; PRAK; MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; p38-regulated/activated protein kinase; PRAK
信號通路： MAPK_ERK_Growth;MAPK_G_Protein;
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:p38 alpha and beta-dependent phosphorylation increases its activity. Activated by stress-related extracellular stimuli; such as H(2)O(2), arsenite, anisomycin TNF alpha and also PMA and the calcium ionophore A23187; but to a lesser extent. In vitro, activated by SQSTM1.,function:Mediates stress-induced small heat shock protein 27 phosphorylation.,PTM:Phosphorylated on Thr-182; which is the regulatory phosphorylation site and is located on the T-loop/loop 12.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Also observed in the nucleus.,subunit:Interacts with SQSTM1.,tissue specificity:Expressed ubiquitously.,
相關(guān)產(chǎn)品： YT3849,YT3848,YP0820,KA4169C,KA1752C
細(xì)胞定位： Cytoplasm. Nucleus. Translocates to the cytoplasm following phosphorylation and activation. Interaction with ERK3/MAPK6 or ERK4/MAPK4 and phosphorylation at Thr-182, activates the protein kinase activity, followed by translocation to the cytoplasm. Phosphorylation by PKA/PRKACA at Ser-115 also induces nuclear export.
組織表達(dá)： Expressed ubiquitously.
科研貨號： PLA004997

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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