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PLZF Monoclonal Antibody

商品貨號(hào)： PLA004993

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

在線咨詢

MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： ZBTB16
蛋白名稱： Zinc finger and BTB domain-containing protein 16
Human_gene_id： 7704
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7704
Human_swiss_prot_no： Q05516
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q05516/entry
特異性： PLZF Monoclonal Antibody detects endogenous levels of PLZF protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： ZBTB16; PLZF; ZNF145; Zinc finger and BTB domain-containing protein 16; Promyelocytic leukemia zinc finger protein; Zinc finger protein 145; Zinc finger protein PLZF
信號(hào)通路： Pathways in cancer;Acute myeloid leukemia;
功能： disease:A chromosomal aberration involving ZBTB16 may be a cause of acute promyelocytic leukemia (APL). Translocation t(11;17)(q32;q21) with RARA.,disease:Defects in ZBTB16 are the cause of skeletal defects genital hypoplasia and mental retardation [MIM:612447]. The disorder is characterized by mental retardation, craniofacial dysmorphism, microcephaly and short stature. Additional features include absence of the thumbs, hypoplasia of the radii and ulnae, additional vertebrae and ribs, retarded bone age and genital hypoplasia.,function:Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,induction:By retinoic acid.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 9 C2H2-type zinc fingers.,subunit:Binds EPN1. Interacts with ZBTB32 and CUL3.,tissue specificity:Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Nucleus, nuclear body .
組織表達(dá)： Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
科研貨號(hào)： PLA004993

PLZF Monoclonal Antibody

Catalog No PLA004993

Product information

發(fā)貨日期： 7
基因名稱： ZBTB16
蛋白名稱： Zinc finger and BTB domain-containing protein 16
Human_gene_id： 7704
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7704
Human_swiss_prot_no： Q05516
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q05516/entry
特異性： PLZF Monoclonal Antibody detects endogenous levels of PLZF protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： ZBTB16; PLZF; ZNF145; Zinc finger and BTB domain-containing protein 16; Promyelocytic leukemia zinc finger protein; Zinc finger protein 145; Zinc finger protein PLZF
信號(hào)通路： Pathways in cancer;Acute myeloid leukemia;
功能： disease:A chromosomal aberration involving ZBTB16 may be a cause of acute promyelocytic leukemia (APL). Translocation t(11;17)(q32;q21) with RARA.,disease:Defects in ZBTB16 are the cause of skeletal defects genital hypoplasia and mental retardation [MIM:612447]. The disorder is characterized by mental retardation, craniofacial dysmorphism, microcephaly and short stature. Additional features include absence of the thumbs, hypoplasia of the radii and ulnae, additional vertebrae and ribs, retarded bone age and genital hypoplasia.,function:Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,induction:By retinoic acid.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 9 C2H2-type zinc fingers.,subunit:Binds EPN1. Interacts with ZBTB32 and CUL3.,tissue specificity:Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Nucleus, nuclear body .
組織表達(dá)： Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
科研貨號(hào)： PLA004993

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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