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Chitotriosidase Monoclonal Antibody

商品貨號(hào)： PLA004728

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書

商品描述

發(fā)貨日期： 7
基因名稱： CHIT1
蛋白名稱： Chitotriosidase-1
Human_gene_id： 1118
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1118
Human_swiss_prot_no： Q13231
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13231/entry
Mouse_swiss_prot_no： Q9D7Q1
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9D7Q1
特異性： Chitotriosidase Monoclonal Antibody detects endogenous levels of Chitotriosidase protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CHIT1; Chitotriosidase-1; Chitinase-1
信號(hào)通路： Amino sugar and nucleotide sugar metabolism;
功能： catalytic activity:Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.,disease:Very high plasma levels of CHIT1 are found in patients with Gaucher disease type 1 (GD I). This can be used as diagnostic aid and to evaluate the success of treatment. Successful therapy brings the CHIT1 activity levels back to normal.,function:Degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.,polymorphism:A 24 bp duplication in exon 10 leads to the activation of an alternative splice site and the production of an inactive protein. About 6% of the population are deficient for CHIT1 activity, while 35% are carriers and show reduced enzyme levels. People with CHIT1 deficiency appear perfectly healthy.,similarity:Belongs to the glycosyl hydrolase 18 family.,similarity:Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.,similarity:Contains 1 chitin-binding type-2 domain.,subcellular location:A small proportion is lysosomal.,subunit:Monomer.,tissue specificity:Detected in spleen. Secreted by cultured macrophages.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Secreted. Lysosome. A small proportion is lysosomal.
組織表達(dá)： Detected in spleen. Secreted by cultured macrophages.
科研貨號(hào)： PLA004728

Chitotriosidase Monoclonal Antibody

Catalog No PLA004728

Product information

發(fā)貨日期： 7
基因名稱： CHIT1
蛋白名稱： Chitotriosidase-1
Human_gene_id： 1118
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1118
Human_swiss_prot_no： Q13231
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13231/entry
Mouse_swiss_prot_no： Q9D7Q1
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9D7Q1
特異性： Chitotriosidase Monoclonal Antibody detects endogenous levels of Chitotriosidase protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CHIT1; Chitotriosidase-1; Chitinase-1
信號(hào)通路： Amino sugar and nucleotide sugar metabolism;
功能： catalytic activity:Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.,disease:Very high plasma levels of CHIT1 are found in patients with Gaucher disease type 1 (GD I). This can be used as diagnostic aid and to evaluate the success of treatment. Successful therapy brings the CHIT1 activity levels back to normal.,function:Degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.,polymorphism:A 24 bp duplication in exon 10 leads to the activation of an alternative splice site and the production of an inactive protein. About 6% of the population are deficient for CHIT1 activity, while 35% are carriers and show reduced enzyme levels. People with CHIT1 deficiency appear perfectly healthy.,similarity:Belongs to the glycosyl hydrolase 18 family.,similarity:Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.,similarity:Contains 1 chitin-binding type-2 domain.,subcellular location:A small proportion is lysosomal.,subunit:Monomer.,tissue specificity:Detected in spleen. Secreted by cultured macrophages.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Secreted. Lysosome. A small proportion is lysosomal.
組織表達(dá)： Detected in spleen. Secreted by cultured macrophages.
科研貨號(hào)： PLA004728

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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