其他名稱: CBX1; CBX; Chromobox protein homolog 1; HP1Hsbeta; Heterochromatin protein 1 homolog beta; HP1 beta; Heterochromatin protein p25; M31; Modifier 1 protein; p25beta
功能: function:Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.,online information:Heterochromatin protein 1 entry,PTM:Not phosphorylated.,similarity:Contains 2 chromo domains.,subcellular location:Unassociated with chromosomes during mitosis.,subunit:Homodimer. Interacts directly with CHAF1A, EMSY, LBR, TIF1/TIF1A and TRIM28/TIF1B PXVXL motif via the chromoshadow domain. Interacts directly with histone H3 methylated at 'Lys-9' via the chromo domain. Interacts with SUV39H1 and SETDB1, SUV420H1 and SUV420H2. Interacts with PRDM6.,tissue specificity:In all adult and embryonic tissues.,
相關產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細胞定位: Nucleus . Unassociated with chromosomes during mitosis.
組織表達: Expressed in all adult and embryonic tissues.
其他名稱: CBX1; CBX; Chromobox protein homolog 1; HP1Hsbeta; Heterochromatin protein 1 homolog beta; HP1 beta; Heterochromatin protein p25; M31; Modifier 1 protein; p25beta
功能: function:Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.,online information:Heterochromatin protein 1 entry,PTM:Not phosphorylated.,similarity:Contains 2 chromo domains.,subcellular location:Unassociated with chromosomes during mitosis.,subunit:Homodimer. Interacts directly with CHAF1A, EMSY, LBR, TIF1/TIF1A and TRIM28/TIF1B PXVXL motif via the chromoshadow domain. Interacts directly with histone H3 methylated at 'Lys-9' via the chromo domain. Interacts with SUV39H1 and SETDB1, SUV420H1 and SUV420H2. Interacts with PRDM6.,tissue specificity:In all adult and embryonic tissues.,
相關產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細胞定位: Nucleus . Unassociated with chromosomes during mitosis.
組織表達: Expressed in all adult and embryonic tissues.
科研貨號: PLA004688
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