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Bmi-1 Monoclonal Antibody

商品貨號： PLA004668

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

在線咨詢

MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： BMI1
蛋白名稱： Polycomb complex protein BMI-1
Human_gene_id： 648
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=648
Human_swiss_prot_no： P35226
Human_swiss_link： http://www.uniprot.org/uniprotkb/P35226/entry
Mouse_swiss_prot_no： P25916
Mouse_swiss_link： http://www.uniprot.org/uniprot/P25916
特異性： Bmi-1 Monoclonal Antibody detects endogenous levels of Bmi-1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： BMI1; PCGF4; RNF51; Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51
功能： disease:Cooperates with the MYC oncogene to produce B-lymphomas.,function:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.,PTM:May be polyubiquitinated; which does not lead to proteasomal degradation.,similarity:Contains 1 RING-type zinc finger.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1/hPRC-H) at least composed of PCGF2/RNF110, BMI1/PCGF4, CBX2/M33, CBX4/PC2, CBX8/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2/RING2. Also component of E3 ubiquitin ligase complex or human polycomb repressive complex 1-like at least composed of PHC2, BMI1, RING1 and RNF2. Interacts with SPOP. Part of a complex consisting of BMI1, CUL3 and SPOP. Interacts with E4F1.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Cytoplasm .
組織表達(dá)： Epithelium,Erythrocyte,Muscle,Thymus,
科研貨號： PLA004668

Bmi-1 Monoclonal Antibody

Catalog No PLA004668

Product information

發(fā)貨日期： 7
基因名稱： BMI1
蛋白名稱： Polycomb complex protein BMI-1
Human_gene_id： 648
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=648
Human_swiss_prot_no： P35226
Human_swiss_link： http://www.uniprot.org/uniprotkb/P35226/entry
Mouse_swiss_prot_no： P25916
Mouse_swiss_link： http://www.uniprot.org/uniprot/P25916
特異性： Bmi-1 Monoclonal Antibody detects endogenous levels of Bmi-1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： BMI1; PCGF4; RNF51; Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51
功能： disease:Cooperates with the MYC oncogene to produce B-lymphomas.,function:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.,PTM:May be polyubiquitinated; which does not lead to proteasomal degradation.,similarity:Contains 1 RING-type zinc finger.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1/hPRC-H) at least composed of PCGF2/RNF110, BMI1/PCGF4, CBX2/M33, CBX4/PC2, CBX8/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2/RING2. Also component of E3 ubiquitin ligase complex or human polycomb repressive complex 1-like at least composed of PHC2, BMI1, RING1 and RNF2. Interacts with SPOP. Part of a complex consisting of BMI1, CUL3 and SPOP. Interacts with E4F1.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Cytoplasm .
組織表達(dá)： Epithelium,Erythrocyte,Muscle,Thymus,
科研貨號： PLA004668

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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