特異性: Cleaved-Factor Xa activated HC (I235) Polyclonal Antibody detects endogenous levels of fragment of activated Factor Xa activated HC protein resulting from cleavage adjacent to I235.
組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源: Polyclonal, Rabbit,IgG
稀釋: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
純化工藝: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度: 1 mg/ml
儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
其他名稱: F10; Coagulation factor X; Stuart factor; Stuart-Prower factor
實測條帶: 30kD
信號通路: Complement and coagulation cascades;
功能: catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.,function:Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.,online information:Factor X entry,PTM:N- and O-glycosylated.,PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.,PTM:The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 Gla (gamma-carboxy-glutamate) domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.,tissue specificity:Plasma; synthesized in the liver.,
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細胞定位: Secreted.
組織表達: Plasma; synthesized in the liver.
科研貨號: PLA004358
Cleaved-Factor Xa activated HC (I235) Polyclonal Antibody
特異性: Cleaved-Factor Xa activated HC (I235) Polyclonal Antibody detects endogenous levels of fragment of activated Factor Xa activated HC protein resulting from cleavage adjacent to I235.
組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源: Polyclonal, Rabbit,IgG
稀釋: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
純化工藝: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度: 1 mg/ml
儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
其他名稱: F10; Coagulation factor X; Stuart factor; Stuart-Prower factor
實測條帶: 30kD
信號通路: Complement and coagulation cascades;
功能: catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.,function:Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.,online information:Factor X entry,PTM:N- and O-glycosylated.,PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.,PTM:The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 Gla (gamma-carboxy-glutamate) domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.,tissue specificity:Plasma; synthesized in the liver.,
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細胞定位: Secreted.
組織表達: Plasma; synthesized in the liver.
科研貨號: PLA004358
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