特異性: Cleaved-SUMO-2/3 (G93) Polyclonal Antibody detects endogenous levels of fragment of activated SUMO-2/3 protein resulting from cleavage adjacent to G93.
組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源: Polyclonal, Rabbit,IgG
稀釋: WB 1:500 - 1:2000. ELISA: 1:20000. IP 1:50-100 Not yet tested in other applications.
純化工藝: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度: 1 mg/ml
儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
其他名稱: SUMO2; SMT3A; SMT3H2; Small ubiquitin-related modifier 2; SUMO-2; HSMT3; SMT3 homolog 2; SUMO-3; Sentrin-2; Ubiquitin-like protein SMT3A; Smt3A
實(shí)測(cè)條帶: 11kD
功能: function:Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.,online information:SUMO protein entry,PTM:Cleavage of precursor form by SENP1 or SENP2 is necessary for function.,PTM:Cleavage of precursor form by SENP1, SENP2 or SENP5 is necessary for function.,PTM:Polymeric chains can be formed through Lys-11 cross-linking.,similarity:Belongs to the ubiquitin family. SUMO subfamily.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:Nuclear bodies.,subunit:Homotrimer (Potential). Crystal packing analysis suggests a possible trimeric assembly, of which the biological significance remains to be determined. Interacts with SAE2 and UBE2I. Covalently attached to a number of proteins. Interacts with PELP1.,subunit:Interacts with SAE2 and UBE2I. Covalently attached to a number of proteins.,tissue specificity:Broadly expressed.,tissue specificity:Expressed predominantly in liver.,
特異性: Cleaved-SUMO-2/3 (G93) Polyclonal Antibody detects endogenous levels of fragment of activated SUMO-2/3 protein resulting from cleavage adjacent to G93.
組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源: Polyclonal, Rabbit,IgG
稀釋: WB 1:500 - 1:2000. ELISA: 1:20000. IP 1:50-100 Not yet tested in other applications.
純化工藝: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度: 1 mg/ml
儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
其他名稱: SUMO2; SMT3A; SMT3H2; Small ubiquitin-related modifier 2; SUMO-2; HSMT3; SMT3 homolog 2; SUMO-3; Sentrin-2; Ubiquitin-like protein SMT3A; Smt3A
實(shí)測(cè)條帶: 11kD
功能: function:Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.,online information:SUMO protein entry,PTM:Cleavage of precursor form by SENP1 or SENP2 is necessary for function.,PTM:Cleavage of precursor form by SENP1, SENP2 or SENP5 is necessary for function.,PTM:Polymeric chains can be formed through Lys-11 cross-linking.,similarity:Belongs to the ubiquitin family. SUMO subfamily.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:Nuclear bodies.,subunit:Homotrimer (Potential). Crystal packing analysis suggests a possible trimeric assembly, of which the biological significance remains to be determined. Interacts with SAE2 and UBE2I. Covalently attached to a number of proteins. Interacts with PELP1.,subunit:Interacts with SAE2 and UBE2I. Covalently attached to a number of proteins.,tissue specificity:Broadly expressed.,tissue specificity:Expressed predominantly in liver.,
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細(xì)胞定位: Nucleus. Nucleus, PML body.
組織表達(dá): Broadly expressed.
科研貨號(hào): PLA004350
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