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Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody

商品貨號(hào)： PLA004290

適應(yīng) 性： 人,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： CASP6
蛋白名稱： Caspase6
Human_gene_id： 839
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=839
Human_swiss_prot_no： P55212
Human_swiss_link： http://www.uniprot.org/uniprotkb/P55212/entry
Mouse_swiss_prot_no： O08738
Mouse_swiss_link： http://www.uniprot.org/uniprot/O08738
Rat_swiss_prot_no： O35397
Rat_swiss_link： http://www.uniprot.org/uniprot/O35397
特異性： Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-6 p18 protein resulting from cleavage adjacent to D179.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
實(shí)測(cè)條帶： 20+35kD
信號(hào)通路： Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;
功能： catalytic activity:Strict requirement for Asp at position P1 and has a preferred cleavage sequence of Val-Glu-His-Asp-|-.,enzyme regulation:Activation is suppressed by phosphorylation at Ser-257.,function:Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.,PTM:Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.,similarity:Belongs to the peptidase C14A family.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Nucleus .
組織表達(dá)： Lung,Lymphocyte,T-cell,
tag： hot
科研貨號(hào)： PLA004290

Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody

Catalog No PLA004290

Product information

基因名稱： CASP6
蛋白名稱： Caspase6
Human_gene_id： 839
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=839
Human_swiss_prot_no： P55212
Human_swiss_link： http://www.uniprot.org/uniprotkb/P55212/entry
Mouse_swiss_prot_no： O08738
Mouse_swiss_link： http://www.uniprot.org/uniprot/O08738
Rat_swiss_prot_no： O35397
Rat_swiss_link： http://www.uniprot.org/uniprot/O35397
特異性： Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-6 p18 protein resulting from cleavage adjacent to D179.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
實(shí)測(cè)條帶： 20+35kD
信號(hào)通路： Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;
功能： catalytic activity:Strict requirement for Asp at position P1 and has a preferred cleavage sequence of Val-Glu-His-Asp-|-.,enzyme regulation:Activation is suppressed by phosphorylation at Ser-257.,function:Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.,PTM:Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.,similarity:Belongs to the peptidase C14A family.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Nucleus .
組織表達(dá)： Lung,Lymphocyte,T-cell,
tag： hot
科研貨號(hào)： PLA004290

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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